Enhanced Expression of p53 Protein in Pityriasis Rubra Pilaris
نویسندگان
چکیده
منابع مشابه
Enhanced expression of p53 protein in pityriasis rubra pilaris.
276 Letters to the Editor Sir, p53 is a phosphoprotein, known since 1992 as a " guardian " of the genome (1, 2). A mutation in the p53 gene coding this protein, which activation protects the organism from tumourigenesis, has been found in more than half of all human tumour types (3). DNA damaging agents induce p53 protein activity, which leads to cell cycle arrest in the G1 or G2 phase and, in ...
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Pityriasis rubra pilaris (PRP) is a rare, chronic papulosquamous skin disorder. The skin lesions rarely have a predilection to sun-exposed areas although it is known that natural sunlight and phototherapy can exacerbate PRP [1–4]. We present a case of a patient suffering from pityriasis rubra pilaris with photoexposed distribution and photosensitivity exclusively to UVB objectively detected by ...
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Pityriasis rubra pilaris (PRP) has always been an intriguing topic ever since its inception. It is a group of chronic disorders characterized by reddish orange plaques with pityriasiform scaling showing follicular keratoses, palmoplantar keratoderma, and sometimes, erythroderma. It occurs all over the world but with racial variations. Its incidence might vary and the age at onset, behavior, cli...
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Pityriasis rubra pilaris is a rare inflammatory disorder characterized by follicular papules on an erythematous base often exhibiting islands of unaffected skin, follicular plugging, and palmoplantar hyperkeratosis. While vitamin A deficiency and autoimmune reactions have been hypothesized as possible etiologies of this condition, pityriasis rubra pilaris-like eruptions secondary to medications...
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ژورنال
عنوان ژورنال: Acta Dermato-Venereologica
سال: 2006
ISSN: 0001-5555
DOI: 10.2340/00015555-0064